Niche Crosstalk: Intercellular Signals at the Hair Follicle

A recent series of papers, including Festa et al. (2011) in this issue, has revealed unexpected interdependent relationships among cell populations residing in and around the hair follicle. These interactions between different lineages of stem cells are crucial for hair follicle growth and cycling and point to a complex crosstalk in stem cell niches

The 2-10 keV XRB dipole and its cosmological implications

The hard X-ray (>2 keV) emission of the local and distant Universe as observed with the HEAO1-A2 experiment is reconsidered in the context of large scale cosmic structure. Using all-sky X-ray samples of AGN and galaxy clusters we remove the dominant local X-ray flux from within a redshift of ~ 0.02. We evaluate the dipolar and higher order harmonic structure in 4 X-ray colours. The estimated dipole anisotropy of the unresolved flux appears to be consistent with a combination of the Compton-Getting effect due to the Local Group motion (dipole amplitude Delta = 0.0042) and remaining large scale structure (0.0023 <~ Delta <~ 0.0085), in good agreement with the expectations of Cold Dark Matter models. The observed anisotropy does however also suggest a non-negligible Galactic contribution which is more complex than current, simple models of >2 keV Galactic X-ray emission. Comparison of the soft and hard colour maps with a harmonic analysis of the 1.5 keV ROSAT all-sky data qualitatively suggests that at least a third of the faint, unresolved ~ 18 deg scale structure in the HEAO1-A2 data may be Galactic in origin. However, the effect on measured flux dipoles is small (<~3%). We derive an expression for dipole anisotropy and acceleration and demonstrate how the dipole anisotropy of the distant X-ray frame can constrain the amplitude of bulk motions of the universe. From observed bulk motions over a local ~ 50 Mpc/h radius volume we determine 0.14 <~ Omega^0.6/b_x(0) <~ 0.59.Comment: 39 pages, Revised version accepted ApJ Main Journal, 3 new Figures + additional tex

On the dimension of subspaces with bounded Schmidt rank

We consider the question of how large a subspace of a given bipartite quantum system can be when the subspace contains only highly entangled states. This is motivated in part by results of Hayden et al., which show that in large d x d--dimensional systems there exist random subspaces of dimension almost d^2, all of whose states have entropy of entanglement at least log d - O(1). It is also related to results due to Parthasarathy on the dimension of completely entangled subspaces, which have connections with the construction of unextendible product bases. Here we take as entanglement measure the Schmidt rank, and determine, for every pair of local dimensions dA and dB, and every r, the largest dimension of a subspace consisting only of entangled states of Schmidt rank r or larger. This exact answer is a significant improvement on the best bounds that can be obtained using random subspace techniques. We also determine the converse: the largest dimension of a subspace with an upper bound on the Schmidt rank. Finally, we discuss the question of subspaces containing only states with Schmidt equal to r.Comment: 4 pages, REVTeX4 forma

Dynamics of the Flow Pattern in a Baffled Mixing Vessel with an Axial Impeller

This paper deals with the primary circulation of an agitated liquid in a flat-bottomed cylindrical stirred tank. The study is based on experiments, and the results of the experiments are followed by a theoretical evaluation. The vessel was equipped with four radial baffles and was stirred with a six pitched blade impeller pumping downwards. The experiments were concentrated on the lower part of the vessel, where the space pulsations of the primary loop, originated due to the pumping action of the impeller. This area is considered to be the birthplace of the flow macroinstabilities in the system – a phenomenon which has been studied and described by several authors. The flow was observed in a vertical plane passing through the axis of the vessel. The flow patterns of the agitated liquid were visualized by means of Al micro particles illuminated by a vertical light knife and scanned by a digital camera. The experimental conditions corresponded to the turbulent regime of agitated liquid flow.It was found that the primary circulation loop is elliptical in shape. The main diameter of the primary loop is not constant. It increases in time and after reaching a certain value the loop disintegrates and collapses. This process is characterized by a certain periodicity and its period proved to be correlated to the occurrence of flow macroinstability. The instability of the loop can be explained by a dissipated energy balance.  When the primary loop reaches the level of disintegration, the whole impeller power output is dissipated and under this condition any flow alteration requiring additional energy, even a very small vortex separation, causes the loop to collapse.

Macro-instabilities of a Suspension in an Axially Agitated Mixing Tank

This paper deals with an experimental assessment of the occurrence of flow macro-instabilities in a mechanically stirred suspension and visual observation of the origination and extinction of macro-vortices. The mean frequency of the occurrence of macro-instabilities in operational conditions was also observed. The experiments were carried out in a cylindrical vessel with an inner diameter of 0.19 m, and an axial stirrer with six pitched 45° blades (PBT) was used. The diameter of the stirrer was equal to half of the vessel diameter. The mean frequencies of the occurrence of macro-instabilities were determined at the stirrer frequency for just suspended conditions in dependence on solids concentration and impeller clearance (height of the stirrer above the bottom of the vessel).Two regions of origin of macro-instabilities and one region of extinction were determined visually. It was found that the mean frequency of occurrence of macro-instabilities increases with increasing stirrer frequency at constant concentration of solids. At constant stirrer speed, the frequency of occurrence of macro-instabilities decreases with increasing concentration of solids. At higher concentration of solids, a sharp change toward lower mean frequencies of macro-instabilities was observed

Discovery of a New 89 Second X-ray Pulsar XTE J1906+09

We report on the discovery of a new pulsating X-ray source during Rossi X-ray Timing Explorer observations of a low galactic latitude field centered at RA (J2000) = 19 hr 05 m 43 s and Dec (J2000) = +08 deg 58 arcmin 48 arcsec. Significant pulsations were detected by both the PCA and HEXTE instruments aboard RXTE at a fundamental period of 89.17 +/- 0.02 seconds, with higher harmonics also visible in the 2-10 keV power spectrum. The folded lightcurve from the source is multiply peaked at lower energies, and changes to single peaked morphology above ~20 keV. The phase averaged spectrum from the source is well fit by strongly absorbed power law or thermal bremsstrahlung spectral models of photon index 1.9 +/- 0.1 or temperature 19.5 +/- 4.6 keV, respectively. The mean neutral hydrogen column density is approximately 10^23 cm^-2, suggesting a distance of >10 kpc to the source and a minimum 2-10 keV X-ray luminosity of 2*10^{35} ergs s^{-1}. By comparison with other pulsars with similar periods and luminosities, we suggest that XTE J1906+09 has a supergiant companion with an underfilled Roche lobe. We speculate further that one of the M stars in a peculiar M star binary system may be the companion.Comment: 14 pages, 2 figures. Accepted by ApJ Letter